Precocious and late increased preeclampsia, maternal results and perinatals
Keywords:
pregnancy, preeclampsia, epidemiologyAbstract
Background: preeclampsia-eclampsia is one of the main causes of maternal and perinatal morbidity and mortality.
Objective: to characterize early and late aggravated preeclampsia according to maternal and perinatal outcomes.
Methodology: descriptive cross-sectional study was performed in the “Mariana Grajales” Gyneco-obstetric Hospital of pregnant women with aggravated pre-eclampsia between 2010 and 2019. The sample consisted of 506 women, it was subdivided into early and late. Frequency distribution tables with absolute and relative values were created. The mean and standard deviation were determined. The Chi Square Test for goodness of fit and the non-parametric Mann Whitney U test were used.
Results: the behavior was similar in the ten years, with a mean of 50.6. The fertile age predominated, with a mean of 27.3 years, in early preeclampsia the mean was 30.6 weeks and in late preeclampsia 37.6 weeks. Most were nulliparous, 242 pregnant, with 207 chronic arterial hypertension. 26.9% had a history of preeclampsia. Maternal complications were minimal. Newborns with normal Apgar scores had an average weight of 2559 grams, while the average weight of dead babies was 1401 grams.
Conclusions: they generally belong to the reproductive age group, the majority are nulliparous, and chronic arterial hypertension is one of the most frequent antecedents found. When pregnancies are closer to term and the weight of the newborns is greater than 2500 grams, the perinatal results are favorable, the opposite is the case in pre-eclampsia of early appearance.
References
1. Mancia G, De Backer G, Dominiczak A. Guidelines for the Management of Arterial Hypertension the Task Force for the management of Arterial Hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC). Hypertens [Internet]. 2018 [cited 2023 Ago 9];25(1):[aprox. 11 p.]. Available from: https://www.google.com/url?sa=t&source=web&rct=j&opi=89978449&url=https://www.portailvasculaire.fr/sites/default/files/docs/2018_esc_esh_guidelines_hta.pdf&ved=2ahUKEwiZqozBst-AAxXLEFkFHRb1BFkQFnoECCEQAQ&usg=AOvVaw1n3G_8hfNbQxS5fuimbHkd
2. Haney F. Danfoth Tratado de obstetricia y ginecología [Internet]. 12th ed. México: Mac Graw-Hill;2015 [citado 9 Ago 2023];2(1):[aprox. 2 p.]. Disponible en: https://www.google.com/url?sa=t&source=web&rct=j&opi=89978449&url=https://www.amazon.com/-/es/Ronald-S-Gibbs/dp/8496921328&ved=2ahUKEwj85ouls9-AAxVPFlkFHYuqAtQQFnoECBMQAQ&usg=AOvVaw2OcQYa6H99mydpsNvbvSEE
3. Moderhauer JS, Sibai BM. Trastornos hipertensivos del embarazo. En: Scout JR, Bibbs R, Beth Kaplan Arthur F, Danfoth H, eds. Tratado de Obstetricia y Ginecología. 12na. ed. México: Mc Graw-Hill; 2015. p. 273-88.
4. Magriples U, Boynton MH, Kershaw TS, Schindler S, Ickovics JR. Blood Pressure Changes during Pregnancy: Impact of Race, Body Mass Index, and Wight Gain. Am J Perinatol. [Internet]. 2019 [cited 2023 Ago 9];30(5):[aprox.2 p.]. Available from: https://www.google.com/url?sa=t&source=web&rct=j&opi=89978449&url=https://escholarship.org/content/qt4987g1z3/qt4987g1z3_noSplash_dbb8c177876f1221b2d9de6a8ccd88a5.pdf&ved=2ahUKEwjasrXns9-AAxWnFVkFHZ8LCi0QFnoECBwQAQ&usg=AOvVaw3uSERTfuPrBq215kyEpEi-
5. Prabhu TR. Cerebrovascular complications in pregnancy and puerperium. J Obstet Gynaecol India [Internet]. 2019 [cited 2023 Ago 9];63(2):[aprox. 12 p.]. Available from: https://www.google.com/url?sa=t&source=web&rct=j&opi=89978449&url=https://www.e-jnc.org/m/makeCookie.php%3Furl%3D/m/journal/view.php%3Fdoi%3D10.18700/jnc.190087&ved=2ahUKEwjxo5eOtN-AAxXdElkFHa3DBf0QFnoECBoQAQ&usg=AOvVaw1dpq88o--tV7LVCnmB-3fU
6. Spaan J, Peeters L, Spaanderman M, Brown M. Cardiovascular Risk Management After a Hypertensive Disorder of Pregnancy. Hypertension. [Internet]. 2023 [citado 2023 Ago 9]; 60(1): [aprox. 4 p.]. Disponible en: https://www.google.com/url?sa=t&source=web&rct=j&opi=89978449&url=https://obgyn.onlinelibrary.wiley.com/doi/10.1002/ijgo.14540&ved=2ahUKEwj1sqG5tN-AAxVGFlkFHdZAAb0QFnoECCAQAQ&usg=AOvVaw0kTmwfbhWRZxJ5d6LAuqxe
7. Noronha-Neto C, Katz L, Coutinho IC, Maia SB, Souza AS, Amorim MM. Clonidine versus captopril for treatment of postpartum very high blood pressure: study protocol for a randomized controlled trial (CLONCAP). Reprod Health. [Internet]. 2023 [citado 2023 Ago 9]; 1(1): [aprox. 5 p.]. Disponible en: https://www.google.com/url?sa=t&source=web&rct=j&opi=89978449&url=https://www.researchgate.net/publication/312957931_Clonidine_versus_Captopril_for_Severe_Postpartum_Hypertension_A_Randomized_Controlled_Trial&ved=2ahUKEwiQs8XbtN-AAxVlFVkFHQLmAzsQFnoECB8QAQ&usg=AOvVaw1eVXyTz39EzUaTo_uzHj8b
8. Dhakal G, Subedi M, Paudel K. Magnesium Sulphate in Management of Severe Pre-eclampsia and Eclampsia. J Nepal Health Res Counc. [Internet]. 2020 [citado 2023 Ago 9]; 10(21): [aprox. 2 p.]. Disponible en: https://www.google.com/url?sa=t&source=web&rct=j&opi=89978449&url=https://amj.journals.ekb.eg/article_91612.html&ved=2ahUKEwiozsr2tN-AAxVOElkFHbEiBfgQFnoECBwQAQ&usg=AOvVaw1Mkzr_UbTZZGitEUPkV11l
9. Sibai BM. Management of late preterm and early-term pregnancies complicated by mild gestational hypertension/pre-eclampsia. Semin Perinatol. [Internet]. 2019 [citado 2023 Ago 9]; 35(5): [aprox. 5 p.]. Disponible en: https://www.google.com/url?sa=t&source=web&rct=j&opi=89978449&url=https://pubmed.ncbi.nlm.nih.gov/21962629/&ved=2ahUKEwiqiumetd-AAxWsF1kFHQ1yCd8QFnoECA0QAQ&usg=AOvVaw3Z4N9WJjiFwQroHOeSzxVZ
10. Clark SL. Strategies for Reducing Maternal Mortality. Semin Perinatol. [Internet]. 2017 [citado 2023 Ago 9]; 2(1): [aprox. 1 p.]. Disponible en: https://www.google.com/url?sa=t&source=web&rct=j&opi=89978449&url=https://pubmed.ncbi.nlm.nih.gov/22280865/&ved=2ahUKEwjf0oTXtd-AAxVhEFkFHSphAQMQFnoECBsQAQ&usg=AOvVaw1L0h_Nh3H10KI8wrV9wDyD
11. Koual M, Abbou H, Carbonnel M, Picone O, Ayoubi JM. Short-term outcome of patients with preeclampsia. Vasc Health Risk Manag. [Internet]. 2019 [citado 2023 Ago 9]; 7(2): [aprox. 14 p.]. Disponible en: https://www.google.com/url?sa=t&source=web&rct=j&opi=89978449&url=https://pubmed.ncbi.nlm.nih.gov/23610524/&ved=2ahUKEwiiwL-Ett-AAxU-F1kFHVemBA0QFnoECBIQAQ&usg=AOvVaw0RlggGreshhmNQMKG3GhoE
12. Duley L, Meher S, Jones L. Drugs for treatment of very high blood pressure during pregnancy. [Internet]. 2018 [citado 2023 Ago 9]: [aprox. 4 p.]. Disponible en: https://www.google.com/url?sa=t&source=web&rct=j&opi=89978449&url=https://pubmed.ncbi.nlm.nih.gov/23900968/&ved=2ahUKEwjbkbSett-AAxVhEFkFHSphAQMQFnoECCAQAQ&usg=AOvVaw2vDA__NBr-w62j-aXs6nJV
13. Barton JR, Barton LA, Istwan NB, et al. Elective delivery at 340/7 to 366/7 weeks’ gestation and its impact on neonatal outcomes in women with stable mild gestational hypertension. [Internet]. 2019 [citado 2023 Ago 9]; 204(44): [aprox. 2 p.]. Disponible en: https://www.google.com/url?sa=t&source=web&rct=j&opi=89978449&url=https://www.sciencedirect.com/science/article/abs/pii/S0002937810010331&ved=2ahUKEwjXn_-3tt-AAxV2FVkFHXHpC1cQFnoECA0QAQ&usg=AOvVaw2rTFHQ3L50AF3NpUwWoB4G
14. Sibai BM, Koch MA, Freire S, et al. The impact of prior preeclampsia on the risk of superimposed preeclampsia and other adverse pregnancy outcomes in patients with chronic hypertension. Am J Obstet Gynecol. [Internet]. 2021 [citado 2023 Ago 9]; 1(6): [aprox. 14 p.]. Disponible en: https://books.google.com.cu/books?id=JL8KEAAAQBAJ&pg=PA283&lpg=PA283&dq=Sibai+BM,+Koch+MA,+Freire+S,+et+al.+The+impact+of+prior+preeclampsia+on+the+risk+of+superimposed+preeclampsia+and+other+adverse+pregnancy+outcomes+in+patients+with+chronic+hypertension.+Am+J+Obstet+Gynecol&source=bl&ots=7a5Vi7BlzV&sig=ACfU3U25-sNCz62zv3uzIs5U5vLM4lpulw&hl=es-419&sa=X&ved=2ahUKEwi8rIjjtt-AAxWnFFkFHSMLC0cQ6AF6BAghEAI
15. Magee LA, Abalos E, von Dadelszen P, Sibai B, Easterling T, Walkinshaw S, et al. How to manage hypertension in pregnancy effectively. Br J Clin Pharmacol. [Internet]. 2020 [citado 2023 Ago 9]; 72(3): [aprox. 14 p.]. Disponible en: https://www.google.com/url?sa=t&source=web&rct=j&opi=89978449&url=https://mednexus.org/doi/10.1097/FM9.0000000000000095&ved=2ahUKEwio_M6St9-AAxXQFVkFHeKgAZYQFnoECCIQAQ&usg=AOvVaw0T9B8Y4UfQ0VYtmQv7CKeW
16. Ganfong Elías A, Nieves Andino A, Simonó Bell NM, González Pérez JM, Díaz MC, Ramírez Robert R, et al. Hipertensión durante la gestación y su repercusión en algunos resultados perinatales en el Hospital "Dr. Agostinho Neto" de Guantánamo. Rev Cubana Obstet Ginecol. [Internet]. 2017 [citado 2023 Ago 9]; 33(3): [aprox. 13 p.]. Disponible en: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S0138-600X2007000300001&lng=es
17. Castillo Fernández FA, Navas Ábalos N. Hipertensión grave que complica el embarazo. Arch Méd Camagüey. [Internet]. 2016 [citado 2023 Ago 9]; 10(1): [aprox. 5 p.]. Disponible en: http://www.amc.sld.cu/amc/2006/v10n1-2006/2138.htm
18. Suárez González JA, Cabrera Delgado MR, Gutiérrez Machado M, Corrales Gutiérrez A, Cairo González V, Rodríguez Royelo L. Resultados de la atención a pacientes con riesgo de preeclampsia-eclampsia. Rev Cubana Obstet Ginecol [Internet]. 2019 [citado 2023 Ago 9]; 38(3): [aprox. 1 p.]. Disponible en: http://scielo.sld.cu/pdf/gin/v38n3/gin03312.pdf
19. Kreskovich J, Sánchez NR, Lezcano MM, Povicick GB, Ruiz Díaz RA, García EO. Hipercolesterolemia y factores de riesgo asociados: prevalencia en estudiantes de medicina entre 18 y 25 años Facultad de Medicina-UNNE. [Internet]. 2020 [citado 2023 Ago 9]: [aprox. 11 p.]. Disponible en: https://www.google.com/url?sa=t&source=web&rct=j&opi=89978449&url=http://www.scielo.org.co/scielo.php%3Fscript%3Dsci_arttext%26pid%3DS0124-00642021000300012&ved=2ahUKEwiO1-qGuN-AAxVZEFkFHUfwClkQFnoECCAQAQ&usg=AOvVaw3nQ2NIm1OP-eQK-BtLU0hl
20. Vázquez-Rodríguez JG, Rico-Trejo EI. Papel del ácido úrico en la preeclampsia-eclampsia Artículo de revisión. [Internet]. 2011 [citado 2023 Ago 9]; 71(5): [aprox. 8 p.]. Disponible en: https://www.google.com/url?sa=t&source=web&rct=j&opi=89978449&url=https://www.medigraphic.com/pdfs/ginobsmex/gom-2011/gom115f.pdf&ved=2ahUKEwi8o6HSt9-AAxWQFlkFHd2OAkkQFnoECA0QAQ&usg=AOvVaw0f75YoW7fFFYJqUvOPdG0Z
Published
How to Cite
Issue
Section
License
Copyright (c) 2026 El autory garantizarán a la revista el derecho de primera publicación de su obra

This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.
Aquellos autores/as que tengan publicaciones con esta revista, aceptan los términos siguientes: Los autores/as conservarán sus derechos de autor y garantizarán a la revista el derecho de primera publicación de su obra, el cuál estará simultáneamente sujeto a la Atribución-NoComercial-CompartirIgual 4.0 Internacional (CC BY-NC-SA 4.0).
Los autores/as podrán adoptar otros acuerdos de licencia no exclusiva de distribución de la versión de la obra publicada (p. ej.: depositarla en un archivo telemático institucional o publicarla en un volumen monográfico) siempre que se indique la publicación inicial en esta revista. Se permite y recomienda a los autores/as difundir su obra a través de Internet (p. ej.: en archivos telemáticos institucionales o en su página web) antes y durante el proceso de envío, lo cual puede producir intercambios interesantes y aumentar las citas de la obra publicada. (Véase El efecto del acceso abierto).













